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NFL Week 10 Picks Against the Spread & Predictions for All 14 Games

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Week 9 was filled with some of the most exciting games of the year thus far, specifically in the early window, and Week 10 looks set to be just as thrilling. We have just four teams on bye once again, which means we have 14 games on deck. We’ve provided our NFL Week 10 picks against the spread for all 14 games and further broken down our best bet for you below.

FanDuel Sportsbook also has a new welcome offer for the opportunity to claim three bonuses at once, and we’ll explain how you can claim yours using any NFL Week 10 predictions, or any betting market for that matter.

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NFL WEEK 10 PICK AGAINST THE SPREAD: Seattle Seahawks -6 (-115 at FanDuel Sportsbook) vs. Washington Commanders

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NFL Week 10 Picks Against The Spread at FanDuel Sportsbook

Before we dive into our best bet, as promised, here are our NFL Week 10 picks against the spread for all 14 games:

Thursday, November 9:

  • Carolina Panthers +3.5 vs. Chicago Bears -3.5

Sunday, November 12:

  • Indianapolis Colts -1.5 vs. New England Patriots +1.5
  • Cleveland Browns +6 vs. Baltimore Ravens -6
  • Green Bay Packers +3 vs. Pittsburgh Steelers -3
  • San Francisco 49ers -3 vs. Jacksonville Jaguars +3
  • New Orleans Saints -2.5 vs. Minnesota Vikings +2.5
  • Houston Texans +6.5 vs. Cincinnati Bengals -6.5
  • Tennessee Titans +1.5 vs. Tampa Bay Buccaneers -1.5
  • Detroit Lions -1.5 vs. Los Angeles Chargers +1.5
  • Atlanta Falcons -1.5 vs. Arizona Cardinals +1.5
  • New York Giants +16.5 vs. Dallas Cowboys -16.5
  • Washington Commanders +6 vs. Seattle Seahawks -6
  • New York Jets -1.5 vs. Las Vegas Raiders +1.5

Monday, November 13:

  • Denver Broncos +7.5 vs. Buffalo Bills -7.5

NFL Week 10 Predictions Featuring Commanders vs. Seahawks

Out of all our NFL Week 10 picks against the spread above, our favorite play is in the late afternoon window out in Seattle with the Seahawks handling the Washington Commanders with ease. It’s clear the oddsmakers aren’t letting Seattle’s blowout loss to the Baltimore Ravens influence them, and we aren’t either.

Rather than going cross-country to take on one of the best teams in the AFC, it will be Washington traveling from coast to coast. The Commanders are likely riding high after a recent win but beating a 2-7 New England Patriots team is far different than facing a team that was just leading the NFC West prior to this past weekend.

The issue the Seahawks ran into was the Ravens running game. Prior to their game against Baltimore, Seattle was a top-10 rushing defense. However, the Ravens have the best running offense in the NFL by a significant margin, so it was going to be a tough test regardless. On the flip side, Washington has the seventh-worst rushing attack.

Therefore, we expect the Seahawks defense to be back in full effect, especially at home. This is an opportunity for Geno Smith and company to put more pressure on the San Francisco 49ers in the division, so the best bet from our NFL Week 10 picks against the spread is on the Seahawks -6 (-115 at FanDuel Sportsbook) over the Commanders.

How to Bet on Our Expert Picks at FanDuel Sportsbook and Get Up to $150 in Bonuses

We mentioned a multi-gifted $150 FanDuel bonus before even going through our NFL Week 10 predictions, and here’s how it works:

  1. Use this link to create a new FD account
  2. Deposit at least $10
  3. Wage $5+ on any pre-game money line

As long as that money line pick wins, you’ll receive $150 in bonus bets, and that’s on top of your normal winnings. So, the best bet from our NFL Week 10 picks against the spread could be the perfect spot. Rather than needing to worry about the Seahawks winning by at least a touchdown, just take them on the money line and still get them at 30/1 odds!

Better yet, it doesn’t end there. You’ll also receive daily profit boosts no matter what, and if you decide none of the NFL Week 10 odds catch your eye and target an NBA team instead, you’ll receive three months of NBA League Pass. All this comes with no FanDuel promo code as well - just sign up here to get started.

NFL Week 10 Schedule & Betting Lines Provided by FanDuel Sportsbook, November 2023

We shared our NFL Week 10 picks against the spread for all 14 games, and here are those matchups paired with the NFL Week 10 odds:

Thursday, November 9:

  • Carolina Panthers +3.5 (-115) vs. Chicago Bears -3.5 (-105)

Sunday, November 12:

  • Indianapolis Colts -1.5 (-110) vs. New England Patriots +1.5 (-110)
  • Cleveland Browns +6 (-115) vs. Baltimore Ravens -6 (-105)
  • Green Bay Packers +3 (-110) vs. Pittsburgh Steelers -3 (-110)
  • San Francisco 49ers -3 (-110) vs. Jacksonville Jaguars +3 (-110)
  • New Orleans Saints -2.5 (-110) vs. Minnesota Vikings +2.5 (-110)
  • Houston Texans +6.5 (-104) vs. Cincinnati Bengals -6.5 (-118)
  • Tennessee Titans +1.5 (-118) vs. Tampa Bay Buccaneers -1.5 (-104)
  • Detroit Lions -1.5 (-105) vs. Los Angeles Chargers +1.5 (-115)
  • Atlanta Falcons -1.5 (-102) vs. Arizona Cardinals +1.5 (-120)
  • New York Giants +16.5 (-115) vs. Dallas Cowboys -16.5 (-105)
  • Washington Commanders +6 (-105) vs. Seattle Seahawks -6 (-115)
  • New York Jets -1.5 (-110) vs. Las Vegas Raiders +1.5 (-110)

Monday, November 13:

  • Denver Broncos +7.5 (-115) vs. Buffalo Bills -7.5 (-105)

Remember, the best way to utilize those odds, our NFL Week 10 predictions or anything for that matter, is to join FanDuel today for your ‘Bet $5, get $150’ bonus plus extra rewards.

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